Reduced Diuretic Dose in Patients Treated With Eplerenone

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Adrenal gland inclusions in patients treated with aldosterone antagonists (Spironolactone/Eplerenone): incidence, morphology, and ultrastructural findings

BACKGROUND Spironolactone is often used to treat hypertension caused by hyperaldosteronism, and as a result, can form concentrically laminated electron dense spironolactone body inclusions within the adrenal gland. Spironolactone bodies have not been investigated in a contemporary cohort or in patients treated with the more recently approved aldosterone antagonist, eplerenone. METHODS Spirono...

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ژورنال

عنوان ژورنال: Circulation: Heart Failure

سال: 2020

ISSN: 1941-3289,1941-3297

DOI: 10.1161/circheartfailure.119.006597